LIU Shuang Lab | A*STAR IMCB

Shuang LIU, Ph.D.
Principal Investigator, Institute of Molecular and Cell Biology, A*STAR

Adjunct Assistant Professor, Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore

Honorary Principal Investigator, Neurobiology Research Programme, Life Sciences Institute, National University of Singapore

Shuang is a National Science Scholarship (BS-PhD) scholar and obtained her undergraduate degree in Chemistry with Medicinal Chemistry from Imperial College London, with final year project supervised by Prof. Ed Tate. She then joined ASTAR’s Experimental Therapeutics Centre, where she identified exploratory and lead-stage compounds against diverse therapeutic targets through fragment-based screening. Shuang completed her DPhil in Chemical Biology at the University of Oxford under the guidance of Prof. Christopher Schofield, focusing on mechanistic and inhibition studies of oncogenic IDH1 variants. She then moved to the Broad Institute of MIT and Harvard/Harvard University for her postdoctoral training in the laboratory of Prof. Stuart Schreiber, where she pioneered the rational discovery of bifunctional and molecular glue-like compounds using DNA-encoded library (DEL) screening. This work was among the first to systematically identify molecular glues (MGs) using a high-throughput platform. Shuang returned to IMCB, ASTAR in 2023 to establish her independent research programme on molecular glue discovery. Her work is supported by the A*STAR Young Achiever Award (2023) and the National Research Foundation Fellowship (2025).

Nafizul KAZI

Scientist

PhD in Chemical Biology

Max Planck Institute, Germany

IMCB Fellowship 2026

MG for Protein Stability

James ZHANG

Scientist

PhD in Chemical Biology

Imperial College London, UK

MG for Signalling Regulation

Dzung NGUYEN

Scientist

PhD in Structure-based Drug Design

Marburg University, Germany

Previous affiliation: Bayer AG

MG for Protein Complex Modulation

Ee Moon CHIN

PhD student

BSc (Hons) in Chemistry

National University of Singapore

A*STAR Graduate Scholarship

MG for RNA Regulation

James LAU

Intern

MPharm in Pharmacy

University College London, UK

MG for Protein Stability

Kaiwen TAN

Intern

BA in Natural Sciences

University of Cambridge, UK

MG for Protein Folding

Benjamin LOKE

Intern

MSci Chemistry with Medicinal Chemistry

Imperial College London, UK

MG for Signalling Regulation

Rosa KAHLER-FOWLER

Intern

BSc in Biology

Humboldt-Universitaet Berlin, Germany

DAAD RISE Programme

MG for Protein Complex Modulation

Alumni

Interns

Oscar Zhao Tianqin (Raffles Institution | 2024, 2025)

Yunke Luo (University of Cambridge | 2024, 2025)

Wendy Wang Kehan (Duke University | 2025)

Lieen Ma (Ningbo University | 2025)

Wencheng Song (University of Cambridge | 2025)

Wenqi Ke (University of Cambridge | 2025)

Ee Moon Chin (National University of Singapore | 2025)

Local Student Attachment Programme (JC)

Daniel Ho Dawei (St. Joseph's Institution | 2024)

Wanqing Ning (Raffles Institution | 2024)

Dylan Chin Hao Ching (Raffles Institution | 2025)

Lewis Tan Kai Shuen (NUS High School of Mathematics and Science | 2025)

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Shuang LIU, Ph.D.Principal Investigator, Institute of Molecular and Cell Biology, A*STAR

Shuang LIU, Ph.D.
Principal Investigator, Institute of Molecular and Cell Biology, A*STAR